Capabilities

Whether your research is basic, applied, advanced or clinical, Tulane has a breadth of research and facility strengths for use and collaboration – as well as cutting-edge technologies available for license.

While Tulane has broad expertise is many areas, below we spotlight a selection of our research strengths. Please contact James or look through Tulane’s website for a comprehensive listing of our research capabilities and related expertise.

 

 

Infectious Disease Therapeutics & Prevention

Tulane engages in a wide range of research activities relating to adult and pediatric infectious diseases, from clinical to epidemiological. Areas of strength include HIV/AIDS, ebola, mycoses, mycobacteria and tropical medicine.

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Cardiovascular & Complex Chronic Conditions

Tulane is focused on the prevention and treatment of adverse events and conditions relating to the continuum of cardiovascular health, i.e.: Hypertension and Diabetes. We are also the home of the Bogalusa Heart Study, and the related wealth of clinical information and expertise derived from years of studying these conditions.

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cancer microscope

 

 

Cancer Biology & Treatment Innovation

In line with Tulane’s philosophy of open engagement, our cancer/oncology program spans boundaries — both within Tulane and at the joint enterprise of the Louisiana Cancer Research Center. Areas of research focus include molecular genetics, tumor biology and signaling, population sciences and prevention, clinical and translational research, cancer health disparities, circadian cancer, leukemia/lymphoma, and prostate, breast and gynecologic cancers.

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neurons

 

 

Neuroscience & Interdisciplinary Research

Neuroscience at Tulane is truly interdisciplinary, and focuses on research areas including neuroendocrinology, neurophysiology, neuropharmacology, and neurosurgery — as well as cognitive, behavioral and developmental neuroscience. Tulane is the home of an innovative teaching laboratory, molecular neuroscience core facilities, and a neurobiotechnology confocal microscopy core.

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transplant dna

 

 

Transplantation & Related Care

Tulane is known throughout the world for an integration of traditional expertise with the latest in cutting-edge technology. We are a respected choice for comprehensive healthcare, and have broad expertise with focus on specific transplant-related areas including stem cells, bone marrow, and adult and pediatric kidney, liver and pancreas transplants.

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While Tulane has a wide range of innovative facilities, below we spotlight a small sub-selection of them. Please contact James or look through Tulane’s website for a comprehensive listing of our innovative facilities and technological capabilities.

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School of Medicine Centers & Institutes

In keeping with the diversity of its missions – education, research, and patient care – Tulane University is continually developing programs of excellence. Our centers and institutes (Including Culinary Medicine, Sickle, Cell, Transgenic Mice, and Medical Simulation and Team Training, among others)will allow Tulane to remain a leading and nationally-recognized medical institution throughout the 21st century.

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Tulane National Primate Research Center

The Tulane National Primate Research Center (TNPRC) has a national mission to improve human and animal health through basic and applied biomedical research. The TNPRC conducts basic and applied biomedical research on human health problems using nonhuman primate models, and investigates nonhuman primate biology and diseases with particular regard to the study of human health problems. In addition to having strong internal research programs, the TNPRC serves as a regional and national resource and center of excellence for biomedical research using nonhuman primates.

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Circadian Biology Center

The primary goal of Tulane’s Circadian Cancer Biology Group is to promote discoveries in the field of biological timing and the circadian system, as they relate to the biology of cancer and the host/cancer balance. This program is also committed to the education and training of researchers at all levels and in diverse disciplines, with circadian biology and cancer as a research focus. Furthermore, the CCBG is dedicated to educating the public regarding the emerging the health issues related to the consequences of circadian disruption on cancer and related diseases, as well as to serve as a resource of information for those seeking to know more about biological timing, circadian rhythms, circadian disruption and cancer.

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Institute of Sports Medicine

The team approach to sports medicine is what sets the Tulane Institute of Sports Medicine apart from the competition. Tulane’s team of experts includes many of the most renowned authorities in the field of sports medicine. Related research and care is performed in an environment unique in the nation and it allows us to access the latest academic research and medical protocols available in the treatment of the athlete – and Tulane sports medicine functions in partnership with the school of medicine, a world leader in the development of state-of–the–art medical technology and innovation and the home to many of the best and brightest medical minds in the world.

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Core Facilities

Tulane University has many research core facilities that are available to research groups/investigators for utilization in their research or collaborative projects. Our care services include SNA Diagnostics & Sequencing, Microscopy, Infectious Disease Aerobiology, Transgenic Mice & Mouse Phenotyping, Molecular Neuroscience, Biospecimines, and Coordinated Instrumentation. More Detail on Tulane Cores.

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This small spotlight of Tulane’s innovative technologies is available for utilization by industry through our technology transfer activities. Please contact James or our Technology Transfer and Intellectual Property Development Office for more information – or to discuss your in-licensing needs so that we can review our research and technology portfolio for you.

 

 

Method of Treating Infections

This patented method of treating infectious diseases using a combination of antibiotics and immunotherapeutics, and effectively treats bacterial infections that are resistant to or failed to respond to standard antibiotic regimens. It offers flexible drug combinations and dosage regimens, demonstrated effectiveness at various stages of exposure and post-infection times, and is applicable to a wide range of bacterial infectious diseases.

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Treatment for Breast Cancer

These Novel Ceramide Analogs show efficacy as potential new treatments for breast cancer – as well as preventative capabilities. Initial indications show potency against chemosensitive and chemoresistant forms of breast cancer. As modified ceramides, these compounds are well tolerated in the human body and ultimately metabolize into prosurvival lipids. Toxicity should be low, and the compounds relatively inexpensive to synthesize.

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Obesity and Diabetes Treatment

These patented compounds are effective antagonists of ghrelin, growth hormone releasing peptide and the growth hormone secretagogue receptor. In addition to obesity and diabetes (Type I and Type II), they have potential efficacy against metabolic syndrome, hypertension and treatment of breast, prostate and pituitary tumors. As peptide compounds, they are relatively short (less than 10 amino acids) and act at the level of the central nervous system. They are generally easy to manufacture and purify, and tend to have very low toxicity profiles.

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Highly Efficient Method of Gene Transfer

This set of modified retrotransposable genetic elements demonstrate higher gene expression than conventional methods, and are suitable for the transfer of customized nucleotide sequences into a genome. This leads to a more efficient integration into the target genome, and has utility for the development of transgenic animal disease models and gene therapies. Highly expressed retrotransposable genetic elements may also be used to develop better models for diseases associated with retrotransposon insertion, including muscular dystrophy and colon cancer.

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Compounds for Repair and Prevention of Damage to Organs Caused by Pharmaceutical Agents

These patent-pending novel pituitary adenylate cyclase-activating polypeptide (PACAP)-like compounds can prevent damage to organs caused by many commonly used therapeutic agents. This includes anticancer agents and immunosuppressive agents, and may also have value in the preservation of cells and organs for transplantation and the treatment or prevention of renal dysfunction. They can potentiate the on-target effects of many anticancer and immunosuppressive agents, be administered before or during treatment with anticancer or immunosuppressive agent, and are capable of being delivered by many minimally invasive routes (including intravenously, intraperitoneally, intranasally, subcutaneously and intramuscularly).

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